崔胜，1973年生，籍贯安徽，病原结构生物学家，病原生物学研究所研究员，博士生导师。1992年考入武汉大学生物化学专业，1997年获得学士学位。2000年在意大利国际高等研究学院（SISSA）、国际遗传工程和生物技术中心（ICGEB）攻读博士学位，从事DNA复制、修复机制研究。2005年慕尼黑大型基因中心进行博士后研究工作，主要研究RIG-I类受体免疫激活机制。2009年回国，2010年升为研究员。

聚焦冠状病毒、小RNA病毒等重要RNA病毒的入侵、复制及其与宿主互作机制；解析关键蛋白质结构，阐明功能及其在感染中的作用，从而发掘潜在药物新靶点；构建抑制剂评价体系，基于靶点设计抗病毒药物，评价候选分子。

1. Gao X#, Tian H#, Zhu K#, Li Q, Hao W, Wang L, Qin B, Deng H*, Cui S* Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic Transport. Nature Communications. 2022 August 15;13:4782 (IF=17.7)

2. Chen P#; Wojdyla JA#; Colasanti O#; Li Z#; Qin B; Wang M; Lohmann V*, Cui S*. Biochemical and structural characterization of hepatitis A virus 2C reveals an unusual ribonuclease activity on single-stranded RNA. Nucleic Acids Research. 2022 Aug 10;50(16):9470-9489. (IF=19.2)

3. Zhang C#, Yang F#, Wojdyla JA, Qin B, Zhang W, Zheng M, Cao W, Wang M, Gao X*, Zheng H*, Cui S*. An anti-picornaviral strategy based on the crystal structure of foot-and-mouth disease virus 2C protein. Cell Reports. 2022 Jul 5;40(1):111030. (IF=10.0)

4. Gao X#, Zhu K#, Qin B#, Olieric V, Wang M, Cui S*. Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions. Nature Communications. 2021 May 14;12(1):2843. (IF=17.7)

5. Gao X#, Qin B#, Chen P#, Zhu K, Hou P, Wojdyla JA, Wang M, Cui S*. Crystal structure of SARS-CoV-2 papain-like protease. Acta Pharm Sin B. 2021 Jan;11(1):237-245. (IF=14.9, ESI, C100)

6. Hao W#, Wojdyla JA, Zhao R, Han R, Das R, Zlatev I, Manoharan M, Wang M, Cui S*. Crystal structure of Middle East respiratory syndrome coronavirus helicase. PLoS Pathogens. 2017 Jun 26;13(6):e1006474. (IF=7.5)

7. Guan H#, Tian J, Qin B, Wojdyla JA, Wang B, Zhao Z, Wang M, Cui S*. Crystal structure of 2C helicase from enterovirus 71. Science Advances. 2017 Apr 28;3(4):e1602573. (IF=15.0)

8. Ou X#, Guan H#, Qin B, Mu Z, Wojdyla JA, Wang M, Dominguez SR, Qian Z*, Cui S*. Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1. Nature Communications. 2017 May 23;8:15216. (IF=17.7)

9. Myong S#*, Cui S#, Cornish PV, Kirchhofer A, Gack MU, Jung JU, Hopfner KP*, Ha T*. Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA. Science. 2009 Feb 20;323(5917):1070-4. (IF=63.7)

10. Cui S#, Eisenächer K#, Kirchhofer A, Brzózka K, Lammens A, Lammens K, Fujita T, Conzelmann KK, Krug A, Hopfner KP*. The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I. Molecular Cell. 2008 Feb 1;29(2):169-79. (IF=19.3)