龚佳男，1986年生，籍贯河南，细胞生物学家，医学实验动物研究所研究员，博士生导师。2004年考入西北农林科技大学生物技术专业，2008年获得学士学位。2008年至2013年在永利集团3044官网欢迎您基础学院进行硕博连读培养，攻读博士学位，从事microRNAs在正常造血和肿瘤中的功能机制研究。2013年底进入澳大利亚伊丽莎白霍尔医学研究所/墨尔本大学生物医学系进行博士后研究工作，主要研究细胞凋亡与肿瘤。2021年聘任为研究员。

主要研究方向包括构建消化道肿瘤疾病模型，利用体外和体内CRISPR文库筛选研究肿瘤癌变机理并寻找治疗新靶点，研究肠道微生态与肿瘤发生发展以及治疗相关机制研究。

1. Ming‑Jie Luo#, Michelle Palmieri#, Chris D Riffkin, Anuratha Sakthianandeswaren, Tirta Mario Djajawi, Yumiko Hirokawa, Victoria Shuttleworth, David H Segal, Christine A White, Duong Nhu, Guillaume Lessene, Margaret Lee, Peter Gibbs, David CS Huang*, Oliver M Sieber* and Jia-Nan Gong*. Define the susceptibility of colorectal cancers to BH3 mimetic compounds. Cell Death Disease. 2020 Sep 10;11(9):735. (IF=6.304）

2. Piers Blombery#, Mary Ann Anderson#, Jia-nan Gong#, Rachel Thijssen#, Richard W.Birkinshaw#, Ella Thompson, Charis E. Teh, Tamia Nguyen, Zhen Xu, Christoffer Flensburg, Thomas E. Lew, Ian J. Majewski, Daniel H.D. Gray, David A. Westerman, Constantine S. Tam, John F. Seymour, Peter E. Czabotar, David C.S. Huang, Andrew W. Roberts. Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia. Cancer Discovery. 2019 Mar;9(3):342-353. (IF=29.497）

3. Jia-nan Gong#, Tiffany Khong, David Segal, Yuan Yao, Chris D. Riffkin, Jean-Marc Garnier, Seong Lin Khaw, Guillaume Lessene, Andrew Spencer, Marco J. Herold, Andrew W. Roberts, David C. S. Huang. Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1. Blood. 2016 Oct 6;128(14):1834-1844. (IF=13.164）

4. Gong JN#, Yu J#, Lin HS#, Zhang XH, Yin XL, Xiao Z, Wang F, Wang XS, Su R, Shen C, Zhao HL, Ma YN, Zhang JW. The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia. Cell Death Differ. 2014 Jan;21(1):100-12. (IF=8.184）

5. Jia-nan Gong#, Jianxiong Li#, Yi Wang#, Changzheng Liu#, Hongyan Jia, Chongliang Jiang, Yuxuan Wang, Min Luo, Hongmei Zhao, Lei Dong, Fang Wang, Junwu Zhang*, Jia Yu*. Characterization of microRNA-29 family expression and investigation of their mechanistic and therapeutic roles in gastric cancer. Carcinogenesis. 2014 Feb; 35(2):497-506. (IF=5.334)

6.  Xiao-Shuang Wang#, Jia-Nan Gong#, Jia Yu, Fang Wang, Xin-Hua Zhang, Xiao-Lin Yin, Zhen-Qing Tan, Zi-Mian Luo, Gui-Hua Yang, Chao Shen, Jun-Wu Zhang*. MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. Blood. 2012 119:4992 -5004. （IF=9.06, C100, ESI）