庾石山，博士，研究员，博士生导师。1993年毕业于中国协和医科大学药物化学专业获理学博士学位，1995-1996年在奥地利维也纳大学作博士后研究。现任药物研究所副所长、“天然药物活性物质与功能”国家重点实验室主任。杰青、国家级重大人才项目入选者（教育部）、国家卫生计生委“有突出贡献的中青年专家”。主要从事天然药物化学和创新药物研究，在中草药（包括濒危动物药材）活性物质的化学研究、新药创制及重大原创药物的成果转化等方面取得系统性和原创性成果。

主要从事濒危动物药材和有毒药用植物中新颖结构药效分子的发现、结构与功能及创新药物研究，具体包括：濒危动物药材药效物质及原创替代品研究；显著活性小分子天然产物的化学生物学研究；基于天然产物的原创药物研究。

1. Sheng Liu, Chunyan Wei, Tian Liu, Shuang-Gang Ma, Chen Chen, Hao Lin, Lianhui Zhang, Heng Wang*, Chong-Jing Zhang* & Shi-Shan Yu*. A heme-activatable probe and its application in the high-throughput screening of Plasmodium falciparum ring-stage inhibitors. Signal Transd. Target. Ther. 2022,7,160. (IF=38.126)

2. Ru-Bing Wang#, Shuang-Gang Ma#*, Cooper S. Jamieson#, Rong-Mei Gao, Yun-Bao Liu, Yong Li, Xiao-Jing Wang, Yu-Huan Li, Kendall N. Houk*, Jing Qu* and Shi-Shan Yu*. Library construction of stereochemically diverse isomers of spirooliganin: their total synthesis and antiviral activity. Chem. Sci. 2021,12,7003-7011. (IF=9.969)

3. Yong Li, Yu-Xun Zhu, Zhao-Xin Zhang, Li Li, Yun-Bao Liu, Jing Qu, Shuang-Gang Ma, Shi-Shan Yu*. Antinociceptive grayanane-derived diterpenoidsfrom flowers of Rhododendron mole. Acta Pharm. Sin. B. 2020,10(6),1073-1082. (IF=11.614)

4. Chunyan Wei#, Cheng-Xiao Zhao#, Sheng Liu#, Jin-Hui Zhao#, Zi Ye, Heng Wang*, Shi-Shan Yu* and Chong-Jing Zhang*. Activity-based protein profiling reveals that secondary-carbon-centered radicals of synthetic 1,2,4-trioxolanes are predominately responsible for modification of protein targets in malaria parasites. Chem. Commun. 2019,55(64),9535-9538. (IF=5.996)

5. Jian Bai#, Dao-Jiang Yan#, Tao Zhang, Yong-Zhi Guo, Yun-Bao Liu, Yi Zou, Man-Cheng Tang, Bing-Yu Liu, Qiong Wu, Shi-Shan Yu*, Yi Tang*, You-Cai Hu*. A Cascade of Redox Reactions Generates Complexityin the Biosynthesis of the Protein Phosphatase-2 Inhibitor Rubratoxin A. Angew. Chem. Int. Edit. 2017,56(17),4782-4786. (IF=12.102, F1000)

6. Chang-Shan Niu, Yong Li, Yun-Bao Liu, Shuang-Gang Ma, Fei Liu, Li Li, Song Xu, Xiao-Jing Wang, Ru-Bing Wang, Jing Qu*, Shi-Shan Yu*. Pierisketolide A and Pierisketones B and C, Three Diterpenes with an Unusual Carbon Skeleton from the Roots of Pieris formosa. Org. Lett. 2017,19(4),906-909. (IF=6.492)

7. Fang-Yi Su, Zheng Zhao, Shuang-Gang Ma, Ru-Bing Wang, Yong Li, Yun-Bao Liu, Yu-Huan Li, Li Li, Jing Qu*, Shi-Shan Yu*. Cnidimonins A-C, Three Types of Hybrid Dimer from Cnidium monnieri: Structural Elucidation and Semisynthesis. Org. Lett. 2017,19,4920-4923. (IF=6.492)

8. Shuang-Gang Ma, Mi Li, Ming-Bao Lin, Li Li, Yun-Bao Liu, Jing Qu*, Yong Li, Xiao-Jing Wang, Ru-Bing Wang, Song Xu, Qi Hou, Shi-Shan Yu*. Illisimonin A, a Caged Sesquiterpenoid with a Tricyclo[5.2.1.01,6]decane Skeleton from the Fruits of Illicium simonsii. Org. Lett. 2017,19,6160-6163. (IF=6.492)

9. Zhong-Hai Tang#, Yun-Bao Liu#, Shuang-Gang Ma#, Li Li, Yong Li, Jian-Dong Jiang, Jing Qu*, Shi-Shan Yu*. Antiviral Spirotriscoumarins A and B: Two Pairs of Oligomeric Coumarin Enantiomers with a Spirodienone-Sesquiterpene Skeleton from Toddalia asiatica. Org. Lett. 2016, 18(19), 5146-5149. (IF=6.579)

10.Ya-Dan Wang#, Xiu-Qi Bao#, Song Xu, Wen-Wen Yu, Sheng-Nan Cao, Jin-Ping Hu, Yong Li, Xiao-Liang Wang, Dan Zhang*, Shi-Shan Yu*. A Novel Parkinson’s Disease Drug Candidate with Potent Anti-neuroinflammatory Effects through the Src Signaling Pathway. J. Med. Chem. 2016,59(19),9062-9079. (IF=6.259)